CJC-1295 DAC – 5 mg

Description

CJC-1295 DAC, also known as growth hormone releasing factor (GRF MOD (1-29) or GHRF), is an analogue of GHRH (growth hormone releasing hormone).

CJC-1295 DAC stimulates HGH and its interaction with GHRH in the body produces a “family” growth hormone (GHR no other peptides cause the production of such a wide spectrum of growth hormones such as CJC-1295). Very valuable and unique characteristics of CJC-1295 is a fact that can influence an increase in the amount of secretory cells and the pituitary growth hormone, which can produce.

The difference between the CJC-1295 and CJC-1295 DAC is that, CJC-1295 DAC is version CJC-1295 with the addition of so-called. Drug Affinity Complex (DAC), which significantly prolong their effects and action. This means that the drug will act in the body much longer than is usual in CJC-1295 (without DAC), namely up to 14 days! Simultaneously, CJC-1295 DAC has such a steep ramp (sharp increase HGH levels) as CJC-1295, but it causes a smoother and more uniform increase HGH levels. Clinical tests it was found that after one injection of CJC-1295 DAC will increase growth hormone in the blood plasma from 3 to 10 times for 6 days, and increased IGF-1 concentrations 1.5-3 times for a period of 9-12 days! Because of the long half-life and stable uniform effects of the CJC-1295 DAC in fitness and bodybuilding becoming more and more popular.

The main effects of CJC-1295 DAC:

• CJC-1295 DAC enhances secretion of growth hormone in the blood
• CJC-1295 DAC helps achieve significant muscle hardness
• CJC-1295 DAC promotes muscle growth and strength
• CJC-1295 DAC helps to efficiently burn fat
• CJC-1295 DAC visibly improves skin quality, has a rejuvenating effect and smooths wrinkles
• CJC-1295 DAC increases bone density
• CJC-1295 DAC effectively strengthens ligaments and joints
• CJC-1295 DAC has a significant positive effect on sleep, regeneration and vitality

The optimal dose of CJC-1295 DAC is 1000 to 2000 mcg per week (4 evenly spaced doses). CJC-1295 DAC is not suitable to separate solo use, and is often combined together with GHRP-6, GHRP-2, Hexarelin or Ipamorelin to achieve a synergistic effect which significantly increases the amount of growth hormone (HGH).

Based on the user experience is the most popular combination of CJC-1295 DAC with GHRP-2 and GHRP-6, and ginseng, which is one of the most to gain muscle mass. Many athletes after this treatment experienced a mean weight increase of 6-9 kg of muscle mass over a period of 6-8 weeks, and the current increase strength and performance of approx. 20%. Also, the old joints and ligaments injury did not hurt, and there was to their gain.


Effects of CJC-1295 on Mice with GHRH Knockout Gene

In a study conducted by Alba et. Al, the efficacy of CJC-1295 was examined against mice with GHRH gene knockout (GHRHKO). While injections with a normal GHRH analog showed no improvement in the growth of the mice, treatment with CJC-1295 was effective in stimulating growth for the mice with GHRH gene knockout (https://journals.physiology.org/doi/full/10.1152/ajpendo.00201.2006?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org).

Three groups of 1-week old mice were treated with 2 microgram of CJC-1295 for 5 weeks. One group was injected every 24 hours, one group every 48 hours, and one group every 72 hours. The researchers measure total body weight, length, and the length of the tibia and femur. It was found that mice injected daily experienced the largest increase in body weight and length and maintained the average body composition and length. Mice receiving treatment every 48 hours or 72 hours showed an increase in femur and tibia length but did not reach full growth. Overall, lean mass and subcutaneous fat remained the same across all three experimental groups.

With treatment of CJC-1295 there was an increase in GH mRNA and total pituitary RNA. This suggests that the somatotroph cells have proliferated which was further confirmed through the use of immunohistochemistry images. Overall, the findings of this study indicate that in mice, daily supplementation with CJC-1295 allows the mice to maintain normal growth patterns, more so than injections every 48 hours or 72 hours.

What is DAC?

The Drug Affinity Complex (DAC) was created by ConjuChem in order to provide protection to the peptides and combat peptide breakdown due to the presence of the peptidase enzyme. In addition to combatting peptide breakdown, the addition of DAC helps to slow down kidney excretion. For both in vivo and ex vivo mechanisms, DAC covalently bonds with albumin in order to resist peptide breakdown. In addition to resisting peptidase cleavage, the covalent bonding of DAC allows for DAC to reach a wider distribution of the compounds throughout the body (https://www.conjuchem.com/technology/dac.html).

Benefits of Using CJC 1295 with DAC

There are many benefits to supplementing CJC-1295 with DAC. While supplementing CJC-1295 with DAC, the half life of the compound is greatly increased, indicating that there is more growth hormone circulating for a longer period of time. Additionally, the use of CJC-1295 has been shown to also lead to an increase in levels of insulin growth factor 1 which has been shown to have positive developmental and anabolic effects (https://canvas.wisc.edu/eportfolios/2985/Home/CJC1295_DAC_or_no_DAC).