Gonadorelin (GnRH) – 10 mg

Description

Gonadorelin (GnRH) – a natural alternative to increase strength and muscle mass in comparison with anabolic steroids based on natural endogenous testosterone and without most of their side effects!
Gonadorelin (GnRH – Gonadotropin releasing hormone), or also known as luteinizing hormone releasing hormone and luliberin is trophic peptide hormone responsible for the release of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. Gonadorelin (GnRH) is synthesized and released from neurones within the hypothalamus. Peptide belongs to a family of gonadotropin releasing hormone. Gonadorelin release represents the first step in the system functioning hypothalamic-pituitary-gonadal axis, which results in men a significant increase in testosterone levels in the blood.

Gonadorelin (GnRH) was first synthesized in 1977, and for his clarifications received Gullemin Roger and Andrew V. Schall Nobel Prize. Gonadorelin GnRH is considered neuro-hormone, because it produces a certain nerve cell. A key area for the production of GnRH is called. “preoptic area” hypothalamus (POA – preoptic area), which contains the majority of neurons negative gonadorelin. After leaching is gonadorelin blood transported to the pituitary, which contains gonadotropic cells with receptors sensitive and responsive to gonadorelin. Binding gonadorelin-in to these receptors subsequently activated in pituitary synthesis and secretion of gonadotropins – luteinizing hormone (LH) and follicle stimulating hormone (FSH).

These processes are controlled by the size and frequency of the GnRH pulses and feedback from androgens and estrogens. Low frequency GnRH pulses lead to FSH secretion, while high frequency pulses of GnRH stimulated LH release. There are also differences in the secretion of GnRH between men and women. For men,Gonadorelin (GnRH) is secreted in pulses at a constant frequency; However, in women with pulse frequency changes during the menstrual cycle, and there is a large increase in the secretion of Gonadorelin (GnRH) just before ovulation. GnRH secretion is pulsating in all vertebrates and is necessary for proper reproductive function. Gonadorelin (GnRH) is degraded by proteolysis in minutes. GnRH activity also influences various sexual behaviors. Elevated levels of GnRH lead women to increase libido and sexual activity. For men, the increase GnRH causes a sharp rise in testosterone levels, accompanied by all its typical strong anabolic and androgenic effects.

Due to these properties becomes gonadotrophin releasing hormone for athletes (especially strength athletes and bodybuilders) very attractive because they can significantly help:

• to build massive muscle mass
• increase strength, endurance and performance
• achieving better and faster recovery

Gonadorelin (GnRH) can either be effectively used as an effective means of PCT for starting the stimulation of testosterone after steroid treatment (as GnRH stimulates the production of human chorio-gonadoptrophin – LH, luteinizing hormone), or as separate anabolic stimulant, through which can be combined with appropriate diet (high-protein diet) and heavy weight training (based on the basic exercises with heavy weights) obtained without problems muscle growth and more than 10 kg new muscle over a period of 4 weeks! These excellent anabolic properties make gonadorelin class stimulant for massive increases in muscle mass, strength and endurance, the results actually comparable to the effect that bringing anabolic steroids, but without most of their potential side effects, because the whole process is done on the basis of its own natural testosterone!

Main results and benefits of the use of Gonadorelin (GnRH):

• Gonadorelin (GnRH) very effectively stimulates the production of testosterone
• When combined with appropriate diet and training gonadorelin allows easily achieved for 4 weeks increases more than 7-8 kg muscle!
• Gonadorelin (GnRH) has a strong anabolic effects, the results obtained are comparable with weaker anabolic steroids (AAS), but without the majority of the potential side effects of AAS, because the entire process takes place on basis of own natural testosterone!
• Gonadotrophin releasing hormone (GnRH) dramatically increases the power, performance and endurance
• Gonadorelin (GnRH) helps to achieve a very good and fast recovery of muscles and body
• Gonadorelin (GnRH) increases libido, sexual activity and potency (fertility in men)
• Gonadorelin (GnRH) is a great PCT remedy to restore natural testosterone formation
• The combination of Gonadorelin (GnRH) with GHR peptides creates a perfect and unique results!

The optimal daily dose of Gonadorelin is: 2-3 mcg per 1 kg of body weight 3 times a day, it is best to take the first dose of Gonadorelin an hour before training, immediately after training second and third at bedtime.

Gonadorelin (GnRH) is well combinable with peptides Hexarelin + CJC1295 DAC or Ipamorelin + CJC1295 DAC. With one of these combinations directly reach brutal increases on muscle mass and strength / extra-excellent results, if your goal is primarily an increase in strength and mass – one of the combinations warmly recommended!

At the same time we are pleased that we can offer the best quality Gonadorelin with more than 99% purity at great prices!

• Effects of Gonadorelin on the Release of Luteinizing Hormone
• In a study conducted by Martinez et. Al, three different variations of gonadorelin were given to cows in order to observe how the peptide would affect various follicular dynamics as well as the release of luteinizing hormone. Gonadorelin was formulated into three different variations for the sake of this study. In the preliminary experiment, nonlactating Holstein cows were randomly chosen to be given an intramuscular injection of gonadorelin diacetate tetrahydrate, the two forms being, Cytorelin (C) and Fertagyl (Fe). The cows then got their blood drawn for an LH analysis at 0, 1, 2, and 4 hours after injection in order to prepare for the second experiment.
• In the second experiment, nonlactating Holstein cows were randomly chosen to be given injections of either Cytorelin, Fertagyl, or Factrel (FA, gonadorelin hydrochloride). The injection was given to the cows 6 to 7 days after their ovulation period and from there, an LH analysis was done 0,1, 2, 4, and 6 hours after treatment, and sonograms were performed twice a day to check for ovulation.
• Following the second experiment, a third experiment was conducted with young, female beef cows where they were randomly selected to receive 1 of 3 of the gonadorelin formulation. From there the researchers waited 6 to 7 days after ovulation and took blood samples for LH analysis at hours 0, 0.5, 1, 1.5, 2, and 4 as well as sonograms of the ovaries.
• Results of this study showed that in experiments 2 and 3, the Holstein cows treated with Cytorelin had higher mean and mean peak plasma LH concentrations. Furthermore, the Holstein cows treated with Cytorelin had a higher number of dominant follicles in an ovulation period than those treated with Fertagyl or Factrel. However, treatment with C versus FE or FA had an unremarkable effect on the beef heifers. Therefore, the study concluded that Cytorelin had the greatest effect on LH release (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC340045/).