The description of this product work will be completed soon ..
ACE-031 is an inhibitor myostatin (GDF-8 - a substance that slows and reduces muscle growth). ACE-031 by blocking of myostatin production supports a faster, more robust and better growth of new muscle mass.
Myostatin (GDF8 = Growth Differentiation Factor 8 = Growth differentiation factor 8) is a protein which in humans is encoded MSTN gene. Myostatin (GDF-8) belongs to a group GDF proteins that inhibit the growth of muscle tissue. Myostatin protein is produced mainly skeletal muscle cells, circulating in the blood and acts on muscle tissue - slows the development of stem cells (inhibits formation of new muscle mass). The exact process remains as yet still unknown.
Myostatin and its related gene was discovered in 1997. Doctors Genetics Se-Jin Lee and Alexander McPherron discovered that the cause of the abnormal and extra-robust muscularity cattle breeds Belgian Blue and Piedmontese are defective myostatin genes (such massive muscles is referred to by the English term "Double muscling ").
Unnaturally mutated mice so that they have little myostatin. The result was that the mutant mice had approx. twice as much muscle as normal mice. These mice were subsequently named as "powerful mice" (Mighty mice). Myostatin gene mutation-u causes the body is unable to produce myostatin, and thus the subsequent muscle growth is not hampered.
These mutations began then use to breed new, more muscular breeds. Genetic mutations in the myostatin-has been observed in races racing greyhound dogs are closely related (Whippet). Individuals with myostatin mutations were far better runners and marked by even a different physique. It is undisputed that the animals lacking myostatin, animals or doped substances that block the activity of myostatin (such as. Follistatin), have a much bigger muscles. Even a 20 percent reduction in myostatin levels has a potentially large impact on the massive muscle development.
In 2004, with the German boy identified mutation of both copies of the myostatin gene. That makes it much stronger than its peers. The boy is growing and becoming more forcefully exceeds their peers. Lack myostatin still does not sign on his health. Doctors they will continue to be careful in case that somehow fundamentally began to increase his vital organs (eg. His heart). His mother, a former sprinter, while a mutation in only one copy of the gene. People with mutations in both copies of the gene MSTN in each cell (homozygotes) leads to a much more marked increase in muscle mass and strength than the ordinary people, and therefore are much stronger than usual. People with mutations in one copy MSTN gene in each cell is also increased muscle mass and strength, but to a lesser extent.
In 2013, the company Acceleron Pharma published results of human studies, in which the sample of 48 healthy women aged 45-75 years old submitted only one injection containing 0.02, 0.05, 0.1, 0.3, 1 or 3 mg of ACE-031 per 1 kg of body weight . 3 mg / kg resulted in them to increase muscle volume by 5 percent, the total muscle mass was increased by 3 percent, and at the same time it seemed that they also reduce the quantity of body fat. Injection ACE-031 reduces the concentration of leptin. This supports the assumption that ACE-031 actively reduces the level of fat. ACE-031 remained in the body after administration in circulation for several weeks, the half-life was determined at 10-15 days.
Inhibition of myostatin-in leads to muscle hyperplasia (growth of new muscle fibers) and substantially greater hypertrophy (growth and increase the existing muscle fibers). For this reason, these products for athletes seeking to increase muscle mass and strength in the future really great potential.
One of the best bodybuilders ever - phenomenal Flex Wheeler has reportedly also lack the myostatin
Effects of ACE-031:
Keep in mind that ACE-031 is a very fragile material! It should be administered separately since the addition of other peptides (in a common syringe) may be damaged. Even with a bottle diluted ACE-031 You should not shake, and just very abrupt antibacterial solution is injected into the vial of ACE-031 can cause damage to the peptides in the upper layers of powder.
Possible side effects:
In clinical studies, which did f. Acceleron Pharma to sample adult boys (volunteers) were observed during treatment with ACE-031 some participants minor nosebleeds, bleeding gums, or small dilated blood vessels in the skin. Most of these side effects, however, has completely disappeared after discontinuation of therapy and discontinuation of ACE-031st
AICAR (Haykaram) is a new extra-stimulant of physical performance that produces excellent results in the increase of physical endurance during long non-stop loads. Strong stimulation of metabolic processes in the body AICAR dramatically increases performance - up to a whopping 50% compared with conventional endurance performance!
Due to the tremendous effect of an increase in performance with AICAR became very popular among athletes as a stimulant phenomenal endurance performance. Another valuable and unique properties of this material is the fact that AICAR helps promote and maintain the physical form even without regular exercise.
Initially, the research was directed peptide armed forces. Scientists were tasked with finding an effective way to increase the resilience of soldiers in extreme conditions. Nor AICAR was not an exception. Peptides in time for its exceptional properties and effects have become very popular and in demand worldwide.
AICAR useful properties:
CJC-1295 also known as growth hormone releasing factor (GRF MOD (1-29) or GHRF) or as Somatokrinin (somatocrinin) is an analog of GHRH (growth hormone releasing hormone).
CJC-1295 stimulates the production of growth hormone, and its interaction with GHRH in the body produces as a result a whole "family" growth hormone (GHRP any other cause producing such a wide spectrum of growth hormones such as CJC-1295). Very valuable and unique properties of CJC-1295 is that it can positively affect the increase in the number of secretory cells, pituitary growth hormone, which can produce.
The main effects of CJC-1295:
The optimal dose of CJC-1295 is 1-3 mcg per 1 kg own weight, and 1-3 servings daily, depending on the desired objectives: For the purposes of combating aging, just to CJC-1295 applied once daily at bedtime. For anabolic purposes it is usually recommended several injections per day (2-3).
CJC-1295 is not suitable for solo use, and is often used in combination with GHRP-6, GHRP-2, Hexarelin or Ipamorelin to achieve a synergistic effect which significantly increases the amount of growth hormone.
In practice it appears, on the basis of experience and feedback of users as the most popular combinations of peptide CJC-1295 together with GHRP-2 and GHRP-6, and ginseng which is one of the best for gaining muscle. Many users - athletes after a cure has experienced an average increase in weight of 6-9 kg of muscle for 6-8 weeks of use, and an increase in strength and performance of approx. 20%. It was also found that the old injuries of joints and ligaments stopped pain, and to their reinforcement.
CJC-1295 DAC, also known as growth hormone releasing factor (GRF MOD (1-29) or GHRF), is an analogue of GHRH (growth hormone releasing hormone).
CJC-1295 DAC stimulates HGH and its interaction with GHRH in the body produces a "family" growth hormone (GHR no other peptides cause the production of such a wide spectrum of growth hormones such as CJC-1295). Very valuable and unique characteristics of CJC-1295 is a fact that can influence an increase in the amount of secretory cells and the pituitary growth hormone, which can produce.
The difference between the CJC-1295 and CJC-1295 DAC is that, CJC-1295 DAC is version CJC-1295 with the addition of so-called. Drug Affinity Complex (DAC), which significantly prolong their effects and action. This means that the drug will act in the body much longer than is usual in CJC-1295 (without DAC), namely up to 14 days! Simultaneously, CJC-1295 DAC has such a steep ramp (sharp increase HGH levels) as CJC-1295, but it causes a smoother and more uniform increase HGH levels. Clinical tests it was found that after one injection of CJC-1295 DAC will increase growth hormone in the blood plasma from 3 to 10 times for 6 days, and increased IGF-1 concentrations 1.5-3 times for a period of 9-12 days! Because of the long half-life and stable uniform effects of the CJC-1295 DAC in fitness and bodybuilding becoming more and more popular.
The main effects of CJC-1295 DAC:
The optimal dose of CJC-1295 DAC is 1000 to 2000 mcg per week (4 evenly spaced doses). CJC-1295 DAC is not suitable to separate solo use, and is often combined together with GHRP-6, GHRP-2, Hexarelin or Ipamorelin to achieve a synergistic effect which significantly increases the amount of growth hormone (HGH).
Based on the user experience is the most popular combination of CJC-1295 DAC with GHRP-2 and GHRP-6, and ginseng, which is one of the most to gain muscle mass. Many athletes after this treatment experienced a mean weight increase of 6-9 kg of muscle mass over a period of 6-8 weeks, and the current increase strength and performance of approx. 20%. Also, the old joints and ligaments injury did not hurt, and there was to their gain.
DES (1-3) IGF-1 is modified, more efficient and improved version of the hormone, IGF-1, with approximately 10 times stronger action and effect as the classical IGF-1! DES (1-3) IGF-1 is particularly suited for massive muscle building and using chiefly shortly before and after training.
It is no secret that IGF-1 is produced in the human body in the liver and in part also in other tissues, but the natural concentration of this hormone is insufficient for achieving the desired results in a significant increase in muscle mass. DES (1-3) IGF-1 is a new generation of IGF-1, which shifts the level and efficiency considerably further. His popularity among athletes and enthusiasts who want as quickly as possible to gain muscle mass because of sharply increasing day by day.
The effectiveness of DES (1-3) IGF-1 has no doubt athletes talk about excellent results. DES (1-3) IGF-1 has a very strong anabolic effects - stimulates the metabolism of amino acids in the body (increases protein synthesis) increases RNA synthesis, promotes fat metabolism, glucose transport and has a strong anti-catabolic effect (protects muscles from decomposition). IGF-1 can stimulate hyperplasia - the growth of new cells. Moreover, the ability to bind to receptors of lactic acid, and enables to start the process of formation of new muscle tissue directly during training and not only afterwards.
DES (1-3) IGF-1 has a very low affinity for binding proteins only 1%, which makes it very effectively usable form of IGF-1, while up to 98% of standard IGF-1 bound to the binding proteins (and remains inactive It is not available for use on skeletal muscles and stimulate its growth). That is the main reason for his secrecy and high efficiency.
Effects DES (1-3) IGF-1:
Differences between DES (1-3) IGF-1 and IGF-1 LR3:
At the recommended dose DES (1-3) IGF-1 has no side effects. The recommended dose for one injection is from 20 to 50 mcg of the DES (1-3) IGF-1 to muscle intramuscularly. The dosing frequency is typically 3-5 times per day, although DES (1-3) IGF-1 may be due to the short life theoretically administered every 20 minutes, if desired (which is very practical terms almost unreal, financially) .As most important thing we could mark a dose of approx. 5 minutes before your workout (which ensure the start of the process of creating new muscle and tissue directly during training), and other benefits after training. As regards the duration of treatment with DES (1-3) IGF-1 may be selected individually and ranges from 4 to 12 weeks. It is recommended to use a break in about 5 weeks.
The second method of administration involves the combined use of PEG-MGF & DES IGF-1 with each other in a common interaction (at which bind to each other processes of proliferation and differentiation), in order to optimize the resulting hyperplasia target local muscle. With this method, a first PEG-MGF administered separately the first 1-4 weeks, then followed by administration of DES IGF-1, for the same number of weeks. Here it should be noted that scientists and athletes are still just learning and exploring how this optimal drug use in this case.
Follistatin-344 significantly increased muscle growth and strength by blocking myostatin (GDF-8 - a protein that inhibit growth of muscle mass). Follistatin-344 is a promising inhibitor of myostatin, with sufficiently safe profile.
Follistatin-344 is also the perfect choice for athletes who are no longer able to exercise regularly, or those who quit sports, but still want to stay in shape, with massive muscles. It has been shown that the smaller the load of muscles and less physical activity, the higher the concentration subsequently myostatin.
Follistatin (also known as activin-binding protein) is an autocrine glycoprotein encoded FST gene which is produced in almost all tissues. Its primary function in the body is bioneutralization members of the TGF-β family of proteins, with special focus on activin and paracrine hormones. Follistatin is a potent inhibitor of myostatin. Original follistatin also worked as an inhibitor of activin, which in turn stimulates secretion of follicle stimulating hormone - FSH (activin regulates the growth and differentiation of nearly all cell types, including the gonads, pituitary and skeletal muscle). For this reason, scientists have developed from the original follistatin derived specific follistatin (follistatin-344), which is preferably capable of blocking the effects of myostatin.
Recent animal experiments, which ended in 2009 showed that the genetic regulation of follistatin levels brought significant results in muscle growth and increase strength. Subsequently, since. 2009 successfully used even by people recorded are the results where daily injections of 100 mcg follistatin-344 brought in individuals weighing 86-87 kg muscle growth approx. 5 kg for 10 days.
Peptide follistatin-344 also has a significant impact on the rejuvenation of tissues. Its distinctive anti-aging effect is comparable with the effect of melatonin and other peptides, positive anti-aging.
With age follistatin production in the body decreases, thus contrary increase side effects of myostatin. Myostatin except that inhibits muscle growth, also regenerates cells in adipose tissue. And because the body starts to regenerate body fat use their own endogenous proteins and free amino acids, and finally the number of muscle fibers with age significantly and steadily falling. That is the real reason why people in old age become "meet and obese" (they accumulate fat), and on the contrary lack of muscle mass.
The effects of follistatin-344:
Recommended use of follistatin-344:
100-200 micrograms follistatin-344 once per day for 10-20 days.
Warning: follistatin should not be used by women.
GHRP-6 peptide which is structurally very similar to its predecessors, GHRP-2. The main difference is that the GHRP-6 increases the appetite in some people. Both peptides can be used together to achieve better synergistic effects. Studies have shown that the highest concentration of growth hormone in the blood to reach the right combination of GHRP-6 and GHRP-2.
GHRP-6 stimulates the pituitary gland to produce GH. GHRP can be used effectively in the treatment of growth hormone deficiency. GHRP-6 is highly effective in increasing blood levels of HGH and IGF-1, which is very convenient for those who want to improve their overall physical, but also mental health status of your body. GHRP-6 stimulates and strengthens the immune system, has a strong anabolic - for significant muscle and strength gains, helping to burn body fat, has a very pronounced anti-aging effect, smooths wrinkles, improves the condition of hair and skin, brings very good night's sleep and excellent regeneration, increases bone strength, has anti-inflammatory effects, it brings a sense of the large influx of energy and vitality, and causing general overall rejuvenation of the body and all of its body tissues.
GHRP-6 can be effectively used in the elderly, very effective anti-aging therapy. GHRP is often used in conjunction with CJC-1295 (GRF 1-29) for pulse amplification of growth hormone. GHRP-6 is to be applied on an empty stomach, at least half an hour before meals. For bodybuilders and athletes GHRP-6 helps very effectively to gain muscle mass, increase strength, recovery and burn fat. GHRP-6 improves energy metabolism. After administration of GHRP-6 occurring rapidly increased appetite, often observed in connection with the leaching of ghrelin stimulation (approximately 20 minutes after injection). Ghrelin is a hormone naturally released in the walls of the stomach, which increases hunger. Due to these characteristics, GHRP-6 sometimes also used to treat cachexia (wasting), eating disorders and obesity.
GHRP-6 is a highly effective for increasing strength, muscle mass and fat burning (making it very popular in bodybuilding and fitness for athletes), for general rejuvenation, strengthening of joints, connective tissue and bone. Increased secretion of HGH in the liver leads to higher amount of IGF-1, which is considered a major metabolite of anabolic growth hormone.
Main benefits and the effects GHRP-6:
Optimal dosing GHRP-6: Subcutaneous or intramuscular injection, the optimal dose of GHRP-6 is 1 mcg / 1kg own body weight 3 times daily. For anabolic purposes (increase strength and muscle mass) can be used GHRP-6 times during the day (3-4 doses) for anti-aging therapy is most important that GHRP-6 enjoyed especially before bedtime.
Storage conditions: 2-8 degrees Celsius (refrigerator).
We introduce Gigarelin - the most sophisticated and effective supplement for athletes, which has been developed!
Gigarelin GHR is a unique product that has a very strong presumption and ambition to bring about a real revolution in the world of sports, health, anti-aging and vitality. Gigarelin overcome their unique effects and complete all existing products and supplements. Gigarelin Rx is the real key to good health, body condition, youthful appearance, regeneration and vitality. Your dreams and ideals of a perfect single-purpose and highly-effective supplement were materialized into this unique product that can completely replace everything else you've tried so far!
Gigarelin is entirely new, revolutionary and unique stimulant tablet formation of natural growth hormone (HGH) in the body. No current stimulant tablet making HGH really can not compete in efficiency and effectiveness with Gigarelin.
Forget all the other existing tablet GHR products, because now there Gigarelin Rx - GHR revolutionary product with incomparably greater effectiveness and efficiency, exceeding even those levels and injecting GHR peptides and synthetic growth hormone (rhGH)!
Main effects and benefits of an innovative product Gigarelin Rx:
Unique features and extreme efficiency of Gigarelin
Gigarelin is the first tablet GH stimulant that is genuine and fully-fledged alternative injectable GHR peptides and recombinant (synthetic) growth hormone (rhGH). The amount of total IGF-1 produced coated positive effects and benefits to the body and the length of the effects (action) even Gigarelin injection peptides, combinations thereof and also synthetic growth hormone is overcome. All other tablet HGH products that have not yet appeared on the market, had a very large and limit degrading drawback: Their effectiveness and absorption rate was very low, almost negligible, reaching values of only 2-8%, which made them very ineffective and inefficient products are actually very weak effect (only this small portion of 2-8% of the total amount of the orally administered active ingredient - GHR peptides actually got into the blood, where it can act, and most of the doses were degraded and damaged already during transition stomach without any effect).
Gigarelin this unfavorable situation changes completely: It is a revolutionary tablet HGH product of an entirely new generation, where thanks to the use of advanced nano and advanced technologies of the future have achieved an extremely high absorption rate at over 90% !! At the same time its unique patented composition can not currently copy, so you can be quite sure that GIGARELIN there is only one, it is a completely unique supplement, and any similar tablet HGH product that is closer excellent effects and properties which have Gigarelin you certainly can not currently produce or offer any other manufacturer or a rival company in the world !!
Gigarelin is more efficient and more powerful stimulant HGH longer-lasting effect, and the process of segregation than growth hormone injection GHR peptides and combinations thereof. The key factor for the anabolic regeneration and the effects of the overall level of production and an important hormone, IGF-1. Scientific studies team of scientists proved that just the overall level of IGF-1 is a straight-proportionally dependent on the length and duration of segregation HGH. For example, tests have found that the injected dose GHR peptide GHRP-2, which causes a significant increase in body HGH levels for 50 to 100 minutes, resulted in substantially lower final levels of IGF-1 compared to the level that could provide two tablets of Gigarelin, which causes the body even more significant increase HGH levels, up to 120 to 180 minutes. Due to prolonged exposure to segregation HGH Gigarelin thus can provide even stronger resulting effects than usual doses of injectable GHR peptides !!
Sophisticated combination of all known and most effective methods of stimulating factors segregation endogenous HGH was achieved in Gigarelin incredible results: After taking Gigarelinu reaches own HGH levels value of 20-40 ng / ml (depending on the number of tablets used and the condition of the individual pituitary) wherein the length of HGH segregation takes 2-3 hours and is up to 40% increase in the level of IGF-1! They are even higher values, which are achieved after standard application injectable GHR peptides or after administration of therapeutic doses of exogenous (synthetic) GH !! Respectively. similar levels of HGH in the blood can be achieved only with large doses GHR injectable peptides or larger dose of rhGH (3 IU or more). Furthermore, a very important fact is that the endogenous growth hormone produced in the body by stimulating of using Gigarelín is more natural for the body and often safer than any exogenous administered artificial growth hormone. Since this is the body's own hormone, the body is several times better accepted, tolerated and tolerated.
HGH important significance for the human body, its general condition and health
HGH (growth hormone) for man is actually a key hormone. Its deficiency is a very negative impact on overall health and rapid deterioration of the condition, performance and appearance of the human body. Production of natural growth hormone with age in the body continuously decreases gradually, and its insufficient level may begin to manifest in humans since the 20 year of life. The main body's response to the decline in HGH is required for anyone aging process. For example: At age 25, the body of a healthy individual produces a daily average of approximately 600 micrograms of endogenous (own) HGH. For 60-year-old man, however, this production will drop to the level of just 90 micrograms per day, which represents less than 15% of healthy young person.
Medical science has clearly demonstrated, and today no one doubts that the decline in the production of HGH is directly related to how quickly your body ages. Aging is of course accompanied by all the well-known negative phenomena: The rapid decline of fitness, endurance and performance, loss of muscle mass and strength accumulation of body fat, impaired regeneration, increased tiredness and fatigue, impaired mental performance and memory, visual aging body - the formation of wrinkles, reducing quality of skin, hair and nails, deterioration of internal organs and overall deterioration of health, and the more frequent occurrence of various diseases, including serious diseases of the cardiovascular system. Additionally, the current unhealthy and often hectic lifestyle contributes to a more rapid decline in the production of HGH, and often low levels of HGH production typical for people in their 60's are today actual for people around 40's!
Gigarelin but is the best possible and most efficient solution in this direction! Thanks Gigarelin you can now maximally suppress and slow down the aging process, respectively. achieved very effectively and significantly rejuvenate your body. From the studies conducted, it is clear that long-term use Gigarelinu human life can be extended of even more than 20-30 years! Or in other words, to look and feel in the 70's like at the age of 45 years!
Gigarelin in many ways significantly overall quality and improve your life. This is the best current universal product to help build muscle mass, excellent physical and mental condition, overall health, physical beauty, youthfulness, excellent regeneration, energy and vitality!
Packaging, use and dosage of Gigarelin
Gigarelin is packaged in a plastic box containing 90 tablets. If we compared the efficacy and overall prudukci HGH levels achieved through use of Gigarelin, recombinant (artificially administered) growth hormone (rhGH), then on the basis of the many clinical tests: 1 tablet of Gigarelin represents equivalently in average about force and effect until 3.33 IU exogenous rhGH, and all without the potential side effects and health risks! If we therefore consider that one pack Gigarelinu represents the power and effect thought to 300 IU rhGH (!!) is the price of Gigarelin 3-4x lower and cheaper than the price of the relevant quantity and quality rhGH vials!
To know the true power and results, which is able to bring Gigarelin and achieve the recommended minimum cycle time / its use is two months. The optimal recommended length of the cycle, however, is six months continuously. Then should follow a break in the use of at least one month, after which you can proceed to the next new cycle.
For anabolic effects is most important to dose before training. For the best antiaging effect and regeneration of the body's most important evening dose of approx. 1-2 hours before bedtime. The recommended daily dose is 2-4 tablets, depending on your weight, height, age and most desired goals and purposes of its use. For the powerful anabolic effect: To bodybuilders we recommend a daily dose of 3-4 tablets. For regeneration and antiaging effect suffices most people daily dose of 2 tablets, or for women with lower body weight (50-60 kg) the daily dose of only 1 tab.
FAQ - frequently asked questions and answers related to Gigarelin Rx:
1) Who is Gigarelin determined, it is also suitable for women?
Gigarelin, although primarily developed and designed especially for athletes and bodybuilders, but it is so great and universal body generally beneficial product with a number of positive effects and benefits that it is as good and excellent for all the other people above 18 years: The hard physical and mentally working ordinary people and non-sportspeople, over women, models, to the sick, the weak and elderly. The difference, of course, will be in the size of the optimal daily dose, which is determined depending on the desired objectives, purpose and individual physical parameters of the individual (age, height, weight).
2) Is Gigarelin safe and has any harmful effects?
Yes course Gigarelin is completely safe product because all processes take place in the body of the natural-based body's own hormones, which itself produces a very well tolerated, and with proper recommended use and dosage Gigarelin absolutely no side effects, which is one of its numerous great features.
3) How is it possible that Gigarelin has several times higher efficiency and enormously more efficient than all other competing tablet GHR / HGH products?
The secrets of the high efficiency and unmatched efficiency of Gigarelin lies in its extremely high absorption capacity and absorbency of active ingredients through the small intestine into the blood stream. To enable it to an orally administered product really work well and operate, is primarily essential prerequisite and an absolute necessity that the maximum proportion of the active substances really got to the blood. When designing of Gigarelin they were utilized years of experience in precision, costly and diligent research team of top scientists and experts in the field of enzymology, oral peptides and biology. So far, there are no other scientific team failed to develop a far less elaborate and sophisticated absorption system, like the one that just uses Gigarelin Rx.
4) Everything is great, but could Gigarelin be cheaper?
Gigarelin is a revolutionary and highly sophisticated product, whose properties compares to no other similar supplement. His challenging research and development was a great investment and costs, because it can be produced at a lower cost, unfortunately, it has to be the product for its manufacturer profitable. However, if you take into account the above-mentioned fact that one package Gigarelinu provides an alternative to the 300 IU rhGH, Gigarelin find that it is actually very affordable. And when account, on all its outstanding and unique effects, be sure you will agree that these are very well invested money in personal health and a better life!
Gonadorelin (GnRH) - a natural alternative to increase strength and muscle mass in comparison with anabolic steroids based on natural endogenous testosterone and without most of their side effects!
Gonadorelin (GnRH - Gonadotropin releasing hormone), or also known as luteinizing hormone releasing hormone and luliberin is trophic peptide hormone responsible for the release of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. Gonadorelin (GnRH) is synthesized and released from neurones within the hypothalamus. Peptide belongs to a family of gonadotropin releasing hormone. Gonadorelin release represents the first step in the system functioning hypothalamic-pituitary-gonadal axis, which results in men a significant increase in testosterone levels in the blood.
Gonadorelin (GnRH) was first synthesized in 1977, and for his clarifications received Gullemin Roger and Andrew V. Schall Nobel Prize. Gonadorelin GnRH is considered neuro-hormone, because it produces a certain nerve cell. A key area for the production of GnRH is called. "preoptic area" hypothalamus (POA - preoptic area), which contains the majority of neurons negative gonadorelin. After leaching is gonadorelin blood transported to the pituitary, which contains gonadotropic cells with receptors sensitive and responsive to gonadorelin. Binding gonadorelin-in to these receptors subsequently activated in pituitary synthesis and secretion of gonadotropins - luteinizing hormone (LH) and follicle stimulating hormone (FSH).
These processes are controlled by the size and frequency of the GnRH pulses and feedback from androgens and estrogens. Low frequency GnRH pulses lead to FSH secretion, while high frequency pulses of GnRH stimulated LH release. There are also differences in the secretion of GnRH between men and women. For men,Gonadorelin (GnRH) is secreted in pulses at a constant frequency; However, in women with pulse frequency changes during the menstrual cycle, and there is a large increase in the secretion of Gonadorelin (GnRH) just before ovulation. GnRH secretion is pulsating in all vertebrates and is necessary for proper reproductive function. Gonadorelin (GnRH) is degraded by proteolysis in minutes. GnRH activity also influences various sexual behaviors. Elevated levels of GnRH lead women to increase libido and sexual activity. For men, the increase GnRH causes a sharp rise in testosterone levels, accompanied by all its typical strong anabolic and androgenic effects.
Due to these properties becomes gonadotrophin releasing hormone for athletes (especially strength athletes and bodybuilders) very attractive because they can significantly help:
Gonadorelin (GnRH) can either be effectively used as an effective means of PCT for starting the stimulation of testosterone after steroid treatment (as GnRH stimulates the production of human chorio-gonadoptrophin - LH, luteinizing hormone), or as separate anabolic stimulant, through which can be combined with appropriate diet (high-protein diet) and heavy weight training (based on the basic exercises with heavy weights) obtained without problems muscle growth and more than 10 kg new muscle over a period of 4 weeks! These excellent anabolic properties make gonadorelin class stimulant for massive increases in muscle mass, strength and endurance, the results actually comparable to the effect that bringing anabolic steroids, but without most of their potential side effects, because the whole process is done on the basis of its own natural testosterone!
Main results and benefits of the use of Gonadorelin (GnRH):
The optimal daily dose of Gonadorelin is: 2-3 mcg per 1 kg of body weight 3 times a day, it is best to take the first dose of Gonadorelin an hour before training, immediately after training second and third at bedtime.
Gonadorelin (GnRH) is well combinable with peptides Hexarelin + CJC1295 DAC or Ipamorelin + CJC1295 DAC. With one of these combinations directly reach brutal increases on muscle mass and strength / extra-excellent results, if your goal is primarily an increase in strength and mass - one of the combinations warmly recommended!
At the same time we are pleased that we can offer the best quality Gonadorelin with more than 99% purity at great prices!
You do not want to go or not go to the gym but would still like to stay in good shape?
Although at first glance sounds like an impossible due to GW-1516 it is indeed possible! GW-1516 is really able to solve this problem, and its use is activated in the body processes that occur during the actual exercise.
GW-1516 (GW-501516, GSK-516) is a modulator of PPAR-β (peroxisome proliferator activated receptor beta), which regulates fat burning through a number of common mechanisms:
This shift changes the body's metabolism in favor of burning fat for energy, while using GW-1516 inhibit muscle catabolism or low blood sugar levels.
GW-1516 also enhances muscle growth, which improves glucose tolerance and reduces the accumulation of fat mass, and even at high fat intake. From which it follows that GW-1516 actually has a strong effect against obesity.
For oral use GW-1516 Endurobol doses of 10 mg daily was found metabolic abnormalities in obese men, probably due to the strong stimulation of fatty acid oxidation. In experimental studies, GW-501516 has proved its ability to increase the level of "good cholesterol" (HDL, alpha-cholesterol) with high density lipoproteins up to 79%. High concentrations of HDL significantly reduces the risk of atherosclerosis and cardiovascular diseases, unlike the "bad cholesterol" (LDL), which in turn increases the risk.
Optimal dosing GW-1516 Endurobol is 5 to 10 mg per day (1-2 tablets). GW-1516 Endurobol has a synergistic effect in combination with AICAR, in clinical studies, the combination showed a much larger increase endurance during exercise as when they used the compound GW-1516 alone.
Even before the Olympics in Beijing in 2008 issued a statement that GW-1516 can be used by athletes as a performance-enhancing substance. Since 2009, however, the GW-1516 added to the list of banned substances. Total time elimination GW-1516 can reach even 40 days or more.
Scientists have found that the growth hormone feature strongly supports burning body fat provides only a short portion at the chain end of the molecule (the small area of less than 10%), namely an area that consists of amino acids 176 to 191. The scientists were able to separate this part of the string growth hormone, which created the peptide HGH fragment 176-191 - extremely effective fat burner, burning very effectively and hard and dense adipose tissue (the toughest and most problematic stationary fat, eg. on the abdomen), which is up to 12.5x effective at burning body fat such as growth hormone itself !!
HGH Fragment is currently one of the most effective fat burners, which exist at all! HGH Fragment significantly improves the lipid profile and lipolytic activity. Slows down lipogenesis (the formation of fatty acids), which means that after a course of action of the peptide (burn excess fat stores) does not occur overhead so. Yo-yo effect and fat will not come back to the original normal. HGH Fragment has a very positive effect on the overall level of physical activity, enhances and speeds up the metabolism and energy production, after its use will feel much more energy and vitality. Regular use of HGH Fragment increases levels of the hormone IGF-1, which has a very strong anabolic and regenerative effects. Simultaneously with all the positive effects described provides HGH fragment still a number of additional benefits: HGH fragment does not adversely affect blood glucose (hypoglycemia causes), does not affect insulin and does not cause proliferation (division) of cells (hyperplasia internal organs is therefore entirely eliminated).
Advantages and main effects of HGH Fragment 176-191:
Optimal and basic daily dose HGH fragment for persons weighing 95 kg at already very easy and effective burning of fat is 1000 mcg, and should be divided into three uniform applications, spaced at least 6 hours:
The recommended duration of use of HGH Fragment 2-3 months, then it is recommended to break. The maximum recommended daily dose for the fastest effect is 2,000 mcg, divided into 3-5 applications.
HGH fragment may be used alone, but is also well combinable with more other peptides. For example, if your goal is in addition to burning fat and improving muscle mass, take HGH Fragment together with CJC-1295 or CJC-1295 DAC, if your goal is to burn fat and present significant growth of new muscle, combine HGH Fragment with Ipamorelin.
Production of IGF-1 (Insulin-like growth factor 1 / insulin-like growth factor 1, Igtropin) in the body stimulates the human growth hormone (HGH, which is a metabolite / precursor and is converted in the liver to said IGF-1). IGF-1 has mostly a very strong anabolic effects and stimulates the metabolism of amino acids in the body - increasing protein synthesis, RNA synthesis increases, promotes fat metabolism and glucose transport, decreases protein breakdown. IGF-1 LR3 is particularly suited for building massive new muscle.
IGF-1 can even stimulate hyperplasia - the growth of new cells. Due to its high - the anabolic properties of IGF-1 won deservedly and rightly so great popularity, especially among bodybuilders and athletes as an effective means of stimulating the growth of muscle mass and strength, and the conversion of fat into energy. IGF-1 consists of 83 amino acids, it is essentially the most powerful anabolic hormone present in the body.
The number of muscle cells after reaching adulthood / end of puberty in the human body stabilizes and then continued to increase. Traditional supplements and exercise can only achieve effects hypertrophy, i.e. the usual increase in size of existing muscle cells, but the number of muscle cells remains unchanged - already during life more match (this also applies when using AAS - anabolic-androgenic steroid, which is the result just only mentioned hypertrophy of muscle cells, ie only increases their volume, but they can not increase their number). However, the use of IGF-1 Long R3 (along with exercise and proper nutrition) can cause so. Hyperplasia of muscle cells, or a real growth of new muscle cells and a real increase in their number in the muscle tissues !!
IGF-1 LR3 is an improved version of the synthetic IGF-1 having prolonged effect. Its comparison with the effects of endogenous IGF-1 produced in the body by the liver, however, remains unclear, and this question many bodybuilders opinions diverge: While some talk about excellent effects of IGF-1 LR3, others call them as weak. Here it should be noted also that buy really good IGF-1 is a significant problem, because the market is literally flooded with its inexpensive but ineffective fakes, which can, in many cases, the real reason why many bodybuilders not achieve significant results, thinking , but that "the received IGF-1". Generally as a rule the results of using AAS (anabolic-androgenic steroids), in combination with IGF-1 LR3 more stable.
Effects of IGF-1 LR3:
The optimal and safe dose IGF LR3 is 50-150 micrograms a day, 7 days a week, recommended cycle time of 2-4 weeks. IGF-1 LR3 remains active in the body for about one day.
LGD-4033 - the strongest and most effective tablet supplement for building muscle mass and strength in the market!
LGD-4033 is a realistic, comparable and most efficient alternative to anabolic-androgenic steroids without their strong androgenic and harmful side effects.
LGD-4033 has a high anabolic activity, thanks to which very effectively helps build robust and also high-quality muscle growth, while at the same time strong support fat burning, excellent recovery and very low, respectively. only a negligible androgenic effects.
Main effects and benefits of LGD-4033 Pro:
Advantages of LGD-4033 compared to anabolic steroids:
LGD-4033 is clearly the most effective, most powerful and most efficient SARMs (selective androgen receptor modulator) for muscle growth and strength of the border all existing and known SARMs. This is an extremely powerful SARM is indeed a very strong anabolic effect that has on muscle building potential comparable with oral anabolic steroids, but far fewer side effects and harmful than they did.
LGD-4033 has an excellent ability to bind to androgen receptors on muscle cells with very high affinity (Ki ~ 1 nM) and selectivity - (ARS connected to androgen receptors only where desired - in muscle tissue), thus can be very effective in attracting new massive and also quality muscle gains, but without current androgenic and minor adverse effects, well known from the use of anabolic-androgenic tablet and injectable steroids (which are especially pleased hepatotoxicity (big burden and harm to the liver), strong to stop the suppression of endogenous testosterone, aromatization, a sharp rise in levels of estrogen and cortisol, a large salt and water retention, acne, oily skin, hair loss, prostate enlargement, excess hair growth, aggression, etc.).
So far, clinical tests have confirmed the high anabolic activity LGD-4033, and its unique ability to build new muscle growth and increase strength. In the test, which was attended by 116 volunteers had only dose of 1 mg LGD-4033 daily brought in men who were taking it for 21 days visible improvement in quantity and quality muscle mass, increase strength and decrease body fat percentage. In another test, it was also demonstrated that even relatively high dose of 22 mg LGD-4033 is administered daily for several weeks did not cause any adverse effects, health problems or stomach problems. In addition to the increase in muscle mass and strength brought the use of LGD-4033 for both men and additional benefits in the form of a very good recovery, decrease body fat, improve overall health and feeling of well-being and vitality.
LGD-4033 thanks to advanced absorb system maximizes the effects and potential of LGD-4033, and is the strongest and most effective supplement tablets for building muscle mass and strength in the market! Some bodybuilders recorded during the 6-week cycle with the use of 15 mg LGD-4033 daily in combination with 3-tablets Gigarelin in overall quality increases and hard muscle up to 12 kg and more! (Of course, while a high daily intake of quality protein, sufficient caloric intake (glycogen supercompensation) and intensive training volume.) LGD-4033 can be taken apart for the purpose of supporting a massive increase in muscle mass very well for definition and improvement, or so. RECOMP (total rebuilding figures for athletic, ie increase muscle mass while burning excess fat), various forms of treatment will vary in dosage and appropriate training.
LGD-4033 has essentially no detrimental effects. The only possible side effect while taking a decrease in the production of testosterone in the body, but that is much weaker and less severe than is the case with steroid use. Rate of suppression of testosterone production is directly dependent on the dose size LGD-4033, at the same time, however, in addition to the decline of endogenous free and total testosterone occurs even decrease unwanted SHBG (Sex hormone-binding globulin - androgens and estrogens binding globulin, inhibit testosterone function). However, it is very interesting to note that there is no reduction in the production of LH (luteinizing hormone) and FSH (follicle stimulating hormone). Thanks to the re-creation of testosterone recovery fast and hassle (not problematic, as after using steroids), and testosterone levels will return to normal at the original value during 1-2 weeks after taking LGD-4033, but recommended minimum PCT . Very valuable property LGD-4033 is that it does not affect the increase in the levels of estrogen and cortisol, and due to its high selectivity (ARS) managed to achieve strong anabolic effect with minimal to negligible current androgenic effects (for comparison: the perfect ratio of anabolic and androgenic activity is at LGD-4033 of less than 10: 1, this ratio is at most steroids testosterone or other hand, contrary to approx. 1: 1).
Recommended use and dosage of LGD-4033 Pro:
Rapid muscle gain - for a massive increase in muscle mass:
Athletes with weight:
While important prerequisite for achieving outstanding results are a high daily intake of quality protein (min. 3 g per 1 kg of body weight per day), sufficient caloric intake (glycogen supercompensation) and intensive training volume with heavy weights.
To achieve maximum results, we recommend using LGD-4033 simultaneously with 2-3 tablets of Gigarelin RX daily.
Cutting - for drawing and burning fat:
The perfect combination for maximum shaping and forming, improving and fat burning is currently taking 2-3 tablets (6-9 mg) LGD-4033 along with a 1-2 tablets Andarine S-4 and 1-2 tablets GW-1516 daily for Cycle 6 12 weeks.
An important prerequisite for achieving good results is the high-protein low-calorie diet (high intake of protein and low-carbohydrate), regular intensive training and cardio.
Muscle density & quality - for muscle density and quality:
The best combination for muscle density and quality is to take 2 tablets (6 mg) LGD-4033 with 2-3 tablets Gigarelin daily for 6-12 weeks cycle.
An important prerequisite for achieving good results is a high-protein diet (high intake of quality protein) and regular intensive training.
RECOMP - for rebuilding the figures for athletic (muscle mass while burning fat):
Men with a body mass:
An important prerequisite for achieving good results is the high-protein low-calorie diet (high intake of protein and low-carbohydrate), regular intensive training and cardio at least 20 minutes at least 3 times a week.
Most efficient and synergistically acting combination for RECOMP the use of LGD-4033, together with 1-2 tablets GW-1516 and 1-2 tablets Gigarelin daily.
In all the above manner and purpose of use is recommended to start and stop taking style pyramid (start with a lower (half or third) daily dose during the first two weeks it gradually increased to full dose + the last two weeks the cycle in reverse to reduce the full dose at a lower dose (one-third) in the last days of use). Clinical tests have not confirmed the influence of LGD-4033 to increase estrogen levels, but still at a daily dose of 4-5 tablets recommend taking an anti-estrogen (eg. Mesterolonum (Proviron, etc.)).
At the same time after a cycle lasting eight weeks or more, or use 4 tablets a day or more is recommended to do a mini-PCT (post-cycle therapy, a small recovery cycle to restore the production of endogenous testosterone), optimally with gonadotrophin releasing hormone (recovery of testosterone to its original level is significantly faster and easier after a cycle with LGD-4033 than with steroids). Tablet PCT possible alternative, instead of injecting gonadorelin (if you want to completely avoid injections) is clomiphene citrate (e.g. Clomid), which stimulates the production of LH and FSH. After the end of treatment should be a pause in the use of LGD-4033 at least, at least in the length of the cycle performed. LGD-4033 is not suitable for women.
Ostarine is for athletes and bodybuilders effective alternative to anabolic steroids. Ostarine combines all the positive properties of anabolic steroids, but without their possible side effects. His strong anabolic action could produce massive muscle and strength gains, yet it is completely safe and harmless to the human body.
Ostarine (also known as Enobosarm, GTX-024 and MK-2866) is a selective androgen receptor modulator (SARM) exhibiting strong anabolic action, consistent with the strength of the anabolic action of natural testosterone (1: 1). Ostarine has high bioavailability in oral and acceptance, therefore, may not be injected. However, the structure does not belong to the steroid and peptide hormones. Originally, this drug was developed in medicine for the treatment of muscular atrophy and osteoporosis.
Ostarine valuable feature is that it does not suppress the production of testosterone in the body's own (no feedback on the level of the natural endogenous testosterone), therefore even after the treatment with the use of Ostarine is no need for hormone replacement therapy. Ostarine can also be used as an excellent tool for muscle mass protection against degradation / decay (has good anti-catabolic effect). Ostarine is completely legal in many countries around the world. For its positive qualities Ostarine becoming rapidly popular among bodybuilders mainly in Europe and the US, where you can buy it in various forms: tablets, as an oral solution, or as a solution for injection.
Effects and advantages of Ostarine (GTX-024):
Dosage: 2-4 tab. daily, as required anabolic effect
TB-500 is a synthetic version of a natural peptide of thymosin beta 4 (TB4) which is present in all human and animal cells.
TB-500 offers athletes many advantages such as improved performance, speed, strength and endurance. Recent tests carried out by the world's leading horse trainers showed that TB-500 has had a huge impact on the results of the competition. These tests together with clinical tests proved the following benefits associated with using TB-500:
TB-500 carries a huge potential for the preparation of athletes. Top athletes often combine the TB-500 with TAD-600 and Esafosfina. This combination gives a synergistic effect for excellent recovery, increase efficiency, speed and endurance.
Dosage TB-500 TB-500 is used at a dose of 300-1000 mcg per day, depending on the desired objectives. Duration of use is 3-4 weeks.